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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES7287.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES7287.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that... more
Product information "Anti-RO60"
disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.,function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Ro 60 kDa family.,similarity:Contains 1 TROVE domain.,subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11., Protein function: RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs (PubMed:18056422, PubMed:26382853). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion (PubMed:26382853). Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853). May play roles in cilia formation and/or maintenance. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300. Cellular localization: Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
Keywords: | Anti-SS-A, Anti-RoRNP, Anti-Ro60 autoantigen, Anti-60 kDa Ro protein, Anti-Ro 60 kDa autoantigen, Anti-RNA-binding protein RO60, Anti-60 kDa ribonucleoprotein Ro, Anti-TROVE domain family member 2, Anti-Sjoegren syndrome antigen A2, RO60 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES7287 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
Immunogen: | The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360 |
MW: | 70 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K11089 | Matching products |
UniProt ID : | P10155 | Matching products |
Gene ID | GeneID 6738 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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