Anti-RNASEN / Drosha

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG57719.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is... more

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Product information "Anti-RNASEN / Drosha"

Protein function: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA- ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double- strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. [The UniProt Consortium]

Keywords:	Anti-RN3, Anti-p241, Anti-DROSHA, Anti-RNase III, Anti-Protein Drosha, Anti-Ribonuclease 3, Anti-Ribonuclease III
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57719

Properties

Application:	FC, ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide from Human RNASEN / Drosha
Format:	Affinity Purified