Anti-Drosha (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00389-T 10 µl (5+ slides) -

3 - 9 business days*

131.00€
IHC-00389 100 µl (50+ slides) -

3 - 9 business days*

493.00€
 
Protein function: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is... more
Product information "Anti-Drosha (IHC)"
Protein function: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA- ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double- strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. [The UniProt Consortium]
Keywords: Anti-RN3, Anti-p241, Anti-DROSHA, Anti-RNase III, Anti-Ribonuclease 3, Anti-Protein Drosha, Anti-Ribonuclease III
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00389

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00389 maps to a region between residue 1324 and 1374 of human double-stranded RNA-specific endoribonuclease using the numbering given in entry NP_037367.3 (GeneID 29102).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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