Anti-RGS2 (Regulator of G Protein Signaling 2, Regulator of G-Protein Signaling 2 24kD, RGS-2, Cell

Anti-RGS2 (Regulator of G Protein Signaling 2, Regulator of G-Protein Signaling 2 24kD, RGS-2, Cell
Item number Size Datasheet Manual SDS Delivery time Quantity Price
R1995-11D.100 100 µg - -

3 - 19 business days*

479.00€
 
Regulators of G-protein signaling (RGSs) are a protein family containing a conserved 120aa domain... more
Product information "Anti-RGS2 (Regulator of G Protein Signaling 2, Regulator of G-Protein Signaling 2 24kD, RGS-2, Cell"
Regulators of G-protein signaling (RGSs) are a protein family containing a conserved 120aa domain (RGS domain), which bind directly to activated G-alpha subunits (Gai and Gaq) and act as GTPase-activating proteins (GAPs). One of these proteins, RGS2, is expressed in thyroid, heart. thyroid, and monocyte-derived DCs. The function of RGS2 as a regulator of Gq is also dependent on regulatory sequences in its amino-terminal domain that direct its localization to the plasma membrane. Recent studies have shown that RGS2 is critical for blood pressure homeostasis, and has been suggested to serve as an effector of the NO-cGMP pathway that promotes vascular relaxation based on studies of aortic rings in vitro. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: Human heart lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-G0S8, Anti-G0/G1 switch regulatory protein 8, Anti-Regulator of G-protein signaling 2, Anti-Cell growth-inhibiting gene 31 protein
Supplier: United States Biological
Supplier-Nr: R1995-11D

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to aa1-50 of human RGS2.
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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