Anti-REST, ID (REST, NRSF, XBR, RE1-silencing transcription factor, Neural-restrictive silencer fact

Anti-REST, ID (REST, NRSF, XBR, RE1-silencing transcription factor, Neural-restrictive silencer fact
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040963.200 200 µl - -

1 - 19 business days

557.00€
 
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses... more
Product information "Anti-REST, ID (REST, NRSF, XBR, RE1-silencing transcription factor, Neural-restrictive silencer fact"
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-NRSF, Anti-REST, Anti-X2 box repressor, Anti-Neural-restrictive silencer factor, Anti-RE1-silencing transcription factor
Supplier: United States Biological
Supplier-Nr: 040963

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: REST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-570 amino acids from the Central region of human REST.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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