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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-AB-81590.50 | 50 µl | - |
7 - 16 business days* |
158.00€
|
|||
E-AB-81590.100 | 100 µl | - |
7 - 16 business days* |
257.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein... more
Product information "Anti-Recombinant p16 ARC, clone R08-2B3"
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. Protein function: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947). [The UniProt Consortium]
Keywords: | Anti-ARPC5, Anti-ARC16, Anti-p16-ARC, Anti-Arp2/3 complex 16 kDa subunit, Anti-Actin-related protein 2/3 complex subunit 5, Recombinant p16 ARC Monoclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-81590 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | R08-2B3 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | A synthetic peptide of human p16 ARC |
Database Information
KEGG ID : | K05754 | Matching products |
UniProt ID : | O15511 | Matching products |
Gene ID | GeneID 10092 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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