Anti-PSMD10

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA002920.25 25 µl -

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166.00€
ATA-HPA002920.100 100 µl -

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370.00€
 
Protein function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of... more
Product information "Anti-PSMD10"
Protein function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 85%
Keywords: Anti-PSMD10, Anti-Gankyrin, Anti-p28(GANK), Anti-26S proteasome regulatory subunit p28, Anti-26S proteasome non-ATPase regulatory subunit 10
Supplier: Atlas Antibodies
Supplier-Nr: HPA002920

Properties

Application: WB, IHC, ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EGCVSNLMVC NLAYSGKLEE LKESILADKS LATRTDQDSR TALHWACSAG HTEIVEFLLQ LGVPVNDKDD AGWSPLHIAA SAGRDEIVKA LLGKGAQVNA VNQNGCTPL (ATA-APrEST74349)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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