Anti-PIN1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-A20	100 µg		-	-	6 - 10 business days*		684.00€

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Protein function: Essential PPIase that regulates mitosis presumably by interacting with NIMA and... more

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Product information "Anti-PIN1"

Protein function: Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. [The UniProt Consortium]

Keywords:	Anti-PIN1, EC=5.2.1.8, Anti-PPIase Pin1, Anti-Rotamase Pin1, Anti-Peptidyl-prolyl cis-trans isomerase Pin1, Anti-Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-A20

Properties

Application:	ELISA, IHC, IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	synthetic peptide corresponding to an internal sequence of human Pin1
MW:	18 kD
Format:	Affinity Purified