Anti-PIN1, Internal

Anti-PIN1, Internal
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG64069.100 100 µg - -

6 - 14 business days*

784.00€
 
Protein function: Essential PPIase that regulates mitosis presumably by interacting with NIMA and... more
Product information "Anti-PIN1, Internal"
Protein function: Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner. [The UniProt Consortium]
Keywords: Anti-PIN1, EC=5.2.1.8, Anti-PPIase Pin1, Anti-Rotamase Pin1, Anti-Peptidyl-prolyl cis-trans isomerase Pin1, Anti-Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG64069

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: rat (Expected: human, mouse, canine)
Immunogen: C-KHSQSRRPSSWRQEKITR
Format: Ammonium Sulfate Precipitated

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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