Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-262A-T 20 µl (2 blots) -

3 - 9 business days*

A304-262A-M 100 µl (10 blots) -

3 - 9 business days*

A304-262A 100 µl (100 µg) -

3 - 9 business days*

Protein function: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong... more
Product information "Anti-PIKE"
Protein function: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion. [The UniProt Consortium]
Keywords: Anti-PIKE, Anti-AGAP2, Anti-GGAP2, Anti-CENTG1, Anti-Cnt-g1, Anti-AGAP-2, Anti-Centaurin-gamma-1, Anti-Phosphatidylinositol 3-kinase enhancer, Anti-GTP-binding and GTPase-activating protein 2, Anti-Arf-GAP with GTPase
Supplier: Bethyl Laboratories
Supplier-Nr: A304-262A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse, Rat)
Immunogen: synthetic peptide. The epitope recognized by A304-262A-T maps to a region between residue 450 to 500 of human Phosphatidylinositol-3-kinase Enhancer using the numbering given in entry NP_055585.1 (GeneID 116986).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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