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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A304-882A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A304-882A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of... more
Product information "Anti-PAN2/USP52"
Protein function: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. Also acts as an important regulator of the HIF1A-mediated hypoxic response. Required for HIF1A mRNA stability independent of poly(A) tail length regulation. [The UniProt Consortium]
Keywords: | Anti-KIAA0710, Anti-PAN deadenylation complex subunit 2, Anti-PAB1P-dependent poly(A)-specific ribonuclease, Anti-Poly(A)-nuclease deadenylation complex subunit 2, Anti-Inactive ubiquitin carboxyl-terminal hydrolase 52 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A304-882A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: rat) |
Immunogen: | synthetic peptide. The epitope recognized by A304-882A-T maps to a region between residue 1 to 50 of human PAB-dependent poly using the numbering given in entry Q504Q3.3 (GeneID 9924). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K12571 | Matching products |
UniProt ID : | Q504Q3 | Matching products |
Gene ID | GeneID 9924 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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