Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-979A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-979A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Its association with the histone methyltransferase MLL2/MLL3 complex is... more
Product information "Anti-PA1"
Protein function: Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1:PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex (PubMed:19124460). However, its function in DNA damage has been questioned. During immunoglobulin class switching in activated B-cells is involved in transcription regulation of downstream switch regions at the immunoglobulin heavy-chain (Igh) locus independently of the MLL2/MLL3 complex. Involved in both estrogen receptor-regulated gene transcription and estrogen-stimulated G1/S cell-cycle transition (PubMed:19039327). Acts as transcriptional cofactor for nuclear hormone receptors. Inhibits the induction properties of several steroid receptors such as NR3C1, AR and PPARG, the mechanism of inhibition appears to be gene-dependent (PubMed:23161582). [The UniProt Consortium]
Keywords: | Anti-GAS, Anti-PAGR1, Anti-C16orf53, Anti-PTIP-associated protein 1, Anti-PAXIP1-associated protein 1, Anti-PAXIP1-associated glutamate-rich protein 1, Anti-Glutamate-rich coactivator interacting with SRC1 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-979A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: horse, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, african elephant, chinese hamster, small-eared galago, thirteen-lined ground squirrel, little brown bat) |
Immunogen: | synthetic peptide. The epitope recognized by A301-979A-T maps to a region between residue 204 and 254 of human PTIP-associated 1 protein using the numbering given in entry NP_078792.1 (GeneID 79447). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K14973 | Matching products |
UniProt ID : | Q9BTK6 | Matching products |
Gene ID | GeneID 79447 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed