Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-44-1107-1 | 1 ml | - |
3 - 11 business days* |
1,250.00€
|
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p57kip2, also known as p57, is a tumor suppressor protein that causes cell cycle arrest at G1 by binding G1 cyclin-CDK complexes. The p57kip2 gene is a potential tumor suppressor target as the gene is located in a chromosomal region implicated in sporadic cancers, Wilms' tumor, and Beckwith Wiedemann syndrome. Anti-p57kip2 labels many cytotrophoblast nuclei and stromal cells in normal placenta, and is useful in differentiating between complete hydatidiform mole and partial hydatidiform mole or hydropic abortion. Protein function: Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. [The UniProt Consortium]
Keywords: | Anti-KIP2, Anti-CDKN1C, Anti-p57Kip2, Anti-Cyclin-dependent kinase inhibitor 1C, Anti-Cyclin-dependent kinase inhibitor p57, Anti-p57 kip2 Monoclonal Antibody (Clone:IHC057) |
Supplier: | Abeomics |
Supplier-Nr: | 44-1107 |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | IHC057 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Format: | Purified |
Database Information
KEGG ID : | K09993 | Matching products |
UniProt ID : | P49918 | Matching products |
Gene ID | GeneID 1028 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Our products are for laboratory research use only: Not for administration to humans!