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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-12-1009-20 | 20 µg | - |
3 - 11 business days* |
373.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential... more
Product information "Anti-NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (clone: rNX2/294) (recombinant monoclonal)"
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. Protein function: Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas. May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter. [The UniProt Consortium]
Keywords: | Anti-NKX2-2, Anti-NKX2.2, Anti-Homeobox protein Nkx-2.2, Anti-Homeobox protein NK-2 homolog B, Recombinant Mouse Monoclonal Antibody to NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)(Clone : rNX2/294) |
Supplier: | Abeomics |
Supplier-Nr: | 12-1009-20 |
Properties
Application: | FC, IF, IHC |
Antibody Type: | Monoclonal |
Clone: | rNX2/294 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse, rat, chicken |
Immunogen: | Human full-length recombinant NKX2.2 protein |
Format: | Purified |
Database Information
KEGG ID : | K08029 | Matching products |
UniProt ID : | O95096 | Matching products |
Gene ID | GeneID 4821 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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