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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2963.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2963.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin... more
Product information "Anti-NIPA"
This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013], Protein function: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Nucleus .
Keywords: | Anti-NIPA, Anti-hNIPA, Anti-ZC3HC1, Anti-HSPC216, Anti-Zinc finger C3HC-type protein 1, Anti-Nuclear-interacting partner of ALK, Anti-Nuclear-interacting partner of anaplastic lymphoma kinase, NIPA rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2963 |
Properties
Application: | WB, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat, monkey |
Immunogen: | The antiserum was produced against synthesized peptide derived from human NIPA. AA range:320-369 |
MW: | 55 kD |
Format: | Antiserum |
Database Information
UniProt ID : | Q86WB0 | Matching products |
Gene ID | GeneID 51530 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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