Anti-MUC1 / Mucin-1 / EMA, clone MUC1/955

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2372IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. Mucin-1... more
Product information "Anti-MUC1 / Mucin-1 / EMA, clone MUC1/955"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. Mucin-1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed in >90% breast carcinomas and metastases. The transgenic protein has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of the protein uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. Mucin-1 antibody is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver. The specific epitope of this Mucin-1 antibody has not yet been determined. Protein function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. [The UniProt Consortium]
Keywords: Anti-PUM, Anti-MUC1, MUC1 / Mucin-1 / EMA Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2372IHC

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: MUC1/955
Conjugate: No
Host: Mouse
Species reactivity: human, mouse
Immunogen: Human milk fat globule membranes
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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