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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V7510SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. MAb VU-4H5 reacts with MUC1, a large... more
Product information "Anti-MUC1 / Mucin-1, clone VU-4H5"
1 mg/ml in 1X PBS, BSA free, sodium azide free. MAb VU-4H5 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of MAb VU-4H5 is APDTR as established with epitope fingerprinting. VU-4H5 preferentially binds to under-glycosylated tumor MUC1. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. Antibody to MUC1 is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver. Protein function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. [The UniProt Consortium]
Keywords: | Anti-PUM, Anti-MUC1, MUC1 Antibody / Mucin-1 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V7510SAF |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | VU-4H5 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Synthetic glycosylated MUC1 60mer tandem repeat NH2-(HGVTSAPDT(GalNAc)RPAPGSTAPPAHG)3-COOH, conjugated to bovine serum albuminn |
Format: | Purified |
Database Information
KEGG ID : | K06568 | Matching products |
UniProt ID : | P15941 | Matching products |
Gene ID | GeneID 4582 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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