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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3962SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. This MAb reacts with MUC1, a large transmembrane... more
Product information "Anti-MUC1 / Mucin-1, clone 115D8"
1 mg/ml in 1X PBS, BSA free, sodium azide free. This MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. It is used as tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Its epitope is destroyed by desialylation i.e. treatment with Neuraminidase. Protein function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. [The UniProt Consortium]
Keywords: | Anti-PUM, Anti-MUC1, MUC1 Antibody / Mucin-1 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3962SAF |
Properties
Application: | FC, IHC (paraffin), IF |
Antibody Type: | Monoclonal |
Clone: | 115D8 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human milk fat globule membranes |
Format: | Purified |
Database Information
KEGG ID : | K06568 | Matching products |
UniProt ID : | P15941 | Matching products |
Gene ID | GeneID 4582 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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