Anti-MC1R

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-15765.20 20 µl -

7 - 16 business days*

71.00€
E-AB-15765.60 60 µl -

7 - 16 business days*

143.00€
E-AB-15765.120 120 µl -

7 - 16 business days*

238.00€
E-AB-15765.200 200 µl -

7 - 16 business days*

396.00€
 
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The... more
Product information "Anti-MC1R"
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. Protein function: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. [The UniProt Consortium]
Keywords: Anti-MSHR, Anti-MC1R, Anti-MSH-R, Anti-MC1-R, Anti-Melanocortin receptor 1, Anti-Melanocyte-stimulating hormone receptor, MC1R Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-15765

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthetic peptide of human MC1R
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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Anti-MC1R Anti-MC1R
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Anti-MC1R Anti-MC1R
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