Anti-MBD2 (isoform 1), Internal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64093.100	100 µg		-	-	6 - 14 business days*		784.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Binds CpG islands in promoters where the DNA is methylated at position 5 of... more

Close menu

Product information "Anti-MBD2 (isoform 1), Internal"

Protein function: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters. [The UniProt Consortium]

Keywords:	Anti-MBD2, Anti-DMTase, Anti-Demethylase, Anti-Methyl-CpG-binding protein MBD2, Anti-Methyl-CpG-binding domain protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64093

Properties

Application:	ELISA, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, rat, canine)
Immunogen:	C-RNDPLNQNKGKPDLN
Format:	Ammonium Sulfate Precipitated