Anti-MBD2

Anti-MBD2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-633A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A301-633A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A301-633A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Binds CpG islands in promoters where the DNA is methylated at position 5 of... more
Product information "Anti-MBD2"
Protein function: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters. [The UniProt Consortium]
Keywords: Anti-MBD2, Anti-DMTase, Anti-Demethylase, Anti-Methyl-CpG-binding protein MBD2, Anti-Methyl-CpG-binding domain protein 2
Supplier: Bethyl Laboratories
Supplier-Nr: A301-633A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Dog, Guinea Pig_10141, Pig, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Duckbill Platypus, Tasmanian Devil, White-tufted-ear Marmoset, Crab-eating Macaque, European Domestic Ferret, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-633A-T maps to a region between residue 361 to 411 of human methyl-CpG binding domain protein 2 using the numbering given in entry NP_003918.1 (GeneID 8932).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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