Anti-MAP Kinase, p38 (MAPK, Erk2, Extracellular Signal Regulated Kinase, RK, CSBP, Mitogen Activated

Anti-MAP Kinase, p38 (MAPK, Erk2, Extracellular Signal Regulated Kinase, RK, CSBP, Mitogen Activated
Item number Size Datasheet Manual SDS Delivery time Quantity Price
M2352-02C.100 100 µl - -

1 - 19 business days

496.00€
 
p38 MAP kinase (MAPK), also called RK (1) or CSBP (2), is the mammalian ortholog of the yeast HOG... more
Product information "Anti-MAP Kinase, p38 (MAPK, Erk2, Extracellular Signal Regulated Kinase, RK, CSBP, Mitogen Activated"
p38 MAP kinase (MAPK), also called RK (1) or CSBP (2), is the mammalian ortholog of the yeast HOG kinase that participates in a signaling cascade controlling cellular responses to cytokines and stress (1-4). Four isoforms of p38 MAP kinase, p38 alpha, beta, gamma (also known as ERK6 or SAPK3) and delta (also known as SAPK4) have been identified. Similar to the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), UV light and growth factors (1-5). MKK3, MKK6 and SEK activate p38 MAP kinase by phosphorylation at Thr180 and Tyr182. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase 2 (3) and to phosphorylate the transcription factors ATF-2 (5), Max (6) and MEF2 (5-8). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: M2352-02C

Properties

Application: WB
Antibody Type: Monoclonal
Clone: 13G9(7D6)
Conjugate: No
Host: Rabbit
Reactivity: Human, Monkey, Mouse, Rat
Immunogen: Synthetic peptide corresponding to human p38alpha MAPK.
Format: Supernatant

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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