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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
M2250-01C.100 | 100 µg | - | - |
3 - 19 business days* |
1,123.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of... more
Product information "Anti-Mannose Binding Protein (Mannan Binding Protein (MBP, Mannan Binding Lectin, MBL)"
Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N-acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q-independent. MBL exhibits complement-dependent antibacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL is synthesized by hepatocytes and has been isolated from the liver or serum of various vertebrate species. Applications: Suitable for use in Western Blot, Immunoassays, Immunohistochemistry, and Flow Cytometry. Can be used for blocking the complement-activating capacity of human MBL. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50, Western Blot: 1:50, Immunohistochemistry (frozen): 1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: | United States Biological |
Supplier-Nr: | M2250-01C |
Properties
Application: | FC, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 9G226 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human MBP. |
Format: | Purified |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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