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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V9038IHC-7ML | 7 ml | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-KRT8 / Cytokeratin 8, clone SPM538"
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*. Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast. Protein function: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. [The UniProt Consortium]
Keywords: | Anti-K8, Anti-KRT8, Anti-CYK8, Anti-CK-8, Anti-Keratin-8, Anti-Cytokeratin-8, Anti-Type-II keratin Kb8, Anti-Keratin, type II cytoskeletal 8, KRT8 Antibody / Cytokeratin 8 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V9038IHC |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | SPM538 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A cytoskeleton preparation containing keratin 8 |
Format: | Purified |
Database Information
KEGG ID : | K07605 | Matching products |
UniProt ID : | P05787 | Matching products |
Gene ID | GeneID 3856 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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