Anti-JMJD2a

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-25296	50 µg		-	-	3 - 15 business days*		742.00€

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JMJD2a (UniProtKB/Swiss Prot entry O75164), belongs to the JMJD2 family of histone demethylases... more

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Product information "Anti-JMJD2a"

JMJD2a (UniProtKB/Swiss Prot entry O75164), belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.

Keywords:	Anti-KDM4A, Anti-JHDM3A, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A, Anti-[histone H3]-trimethyl-L-lysine(9) demethylase 4A, Anti-[histone H3]-trimethyl-L-lysine(36) demethylase 4A,
Supplier:	BPS Bioscience
Supplier-Nr:	25296

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Species reactivity:	human
Immunogen:	human JMJD2a (Jumonji domain containing 2a), using a KLH conjugated synthetic peptide containing a sequence from the central part of the protein.
Format:	Affinity Purified