36 products were found matching "O75164"!

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no...

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: KDM4A. Antigen Species: Human

Replaces JMJD2A, #BPS-50103, a.a. 1-480. Human JMJD2A, also known as JHDM3A and KDM4A (GenBank Accession No. NM_014663) (amino-acids 1-350) with N-terminal His-tag, MW=42 kDa, expressed in an E.coli expression system.

Jumonji Domain Containing 2A (JMJD2A) is a lysine-specific demethylase that catalyzes the demethylation of histone H3 at lysine residues 9 and 36 and histone H1.4 at lysine residue 26. It is composed of the JmjN N-terminal domain, JmjC catalytic domain, two plant homeodomains (PHDs), and two tudor domains that...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KDM4A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KDM4A. Next,...

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no...

JMJD2a (UniProtKB/Swiss Prot entry O75164), belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no...

The JMJD2A Homogeneous Assay Kit is designed to measure activity of the JMJD2A using purified enzyme complex or cell extracts containing JMJD2A, using AlphaScreen or AlphaLISA technology. JMJD2A is a JmjC-domain protein that exhibits demethylation activity toward H3-K9Me3 and H3-K36Me3. The JMJD2A Homogeneous Assay...

Jumonji Domain Containing 2A (JMJD2A) is a lysine-specific demethylase that catalyzes the demethylation of histone H3 at lysine residues 9 and 36 and histone H1.4 at lysine residue 26. It is composed of the JmjN N-terminal domain, JmjC catalytic domain, two plant homeodomains (PHDs), and two tudor domains that...

Methylation of lysine residues of core histones plays a critical role in the regulation of gene expression. Jumonji domain containing 2A (JMJD2A) is the first reported trimethyllysine-specific histone demethylase. It catalyzes the demethylation of trimethylated forms of histone at lysine residues 9 and 36. Like...

Anti-JMJD2A Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with JMJD2A from other sources has not been determined. Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a...

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no...