126 products were found matching "K06709"!

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PFI-90
PFI-90

Item number: Cay40120-250

PFI-90 is an inhibitor of lysine demethylases (KDMs). It inhibits KDM3B, KDM4B, KDM5A, and KDM6B by 46.8 to 87.1% when used at a concentration of 10 µM. PFI-90 induces cell death in SJSA-1 osteosarcoma and TC-32 Ewing's sarcoma cancer cells (IC50s = 2 and 1 µM, respectively).Formal Name: 2-(2-pyridinyl)hydrazide,...
Keywords: 2-(2-pyridinyl)hydrazide, 2-pyridinecarboxylic acid
Application: KDM (lysine demethylase) inhibitor
CAS 53995-62-3
MW: 214.2 D
From 64.00€ *
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Anti-KDM4A / JMJD2A / JHDM3A
Anti-KDM4A / JMJD2A / JHDM3A

Item number: NSJ-RQ7088

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Lysine-specific demethylase 4A is an enzyme that in humans is encoded by the KDM4A gene. This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two...
Keywords: Anti-KDM4A, Anti-JHDM3A, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A, Anti-[histone...
Application: WB, IHC (paraffin), FC, Direct ELISA
Host: Rabbit
Species reactivity: human, mouse, rat
755.00€ *
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-10 %
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Human KDM4A (Lysine Specific Demethylase 4A) ELISA Kit
Human KDM4A (Lysine Specific Demethylase 4A) ELISA Kit

Item number: ELK-ELK4412.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KDM4A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KDM4A. Next,...
Keywords: KDM4A, JHDM3A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A, [histone H3]-trimethyl-L-lysine(9)...
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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Anti-JMJD2A
Anti-JMJD2A

Item number: A300-861A

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no...
Keywords: Anti-KDM4A, Anti-JHDM3A, EC=1.14.11.-, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A,...
Application: WB, IP
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
Anti-JMJD2B
Anti-JMJD2B

Item number: A301-478A

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and...
Keywords: Anti-KDM4B, Anti-JHDM3B, EC=1.14.11.-, Anti-Lysine-specific demethylase 4B, Anti-Jumonji domain-containing protein 2B,...
Application: WB, IP
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
KDM4D-IN-1
KDM4D-IN-1

Item number: Cay37431-1

KDM4D-IN-1 is an inhibitor of the histone demethylase jumonji domain-containing 2D (JMJD2D, IC50 = 0.41 µM). It is selective for JMJD2D over JMJD1B, JMJD2B, and jumonji AT rich interactive domain-containing protein 1A (JARID1A, IC50s = >10 µM for all). KDM4D-IN-1 (0.5 µM) decreases the colony formation, migration,...
Keywords: KDM4D Inhibitor 1, 4,5-dihydro-2-methyl-5-oxo-pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile
Application: JMJD2D (KDM4) inhibitor
CAS 2098902-68-0
MW: 225.2 D
From 122.00€ *
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Anti-JMJD2C
Anti-JMJD2C

Item number: A300-885A

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no...
Keywords: Anti-GASC1, Anti-KDM4C, EC=1.14.11.-, Anti-GASC-1 protein, Anti-Lysine-specific demethylase 4C, Anti-Jumonji...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
N-Oxalylglycine
N-Oxalylglycine

Item number: Cay13944-5

The jumonji domain-containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are...
Keywords: NOG, N-(carboxycarbonyl)-glycine
Application: PHD1/PHD2 inhibitor
CAS 5262-39-5
MW: 147.1 D
From 43.00€ *
Review
Anti-JMJD2B
Anti-JMJD2B

Item number: A301-477A

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and...
Keywords: Anti-KDM4B, Anti-JHDM3B, EC=1.14.11.-, Anti-Lysine-specific demethylase 4B, Anti-Jumonji domain-containing protein 2B,...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
JMJD2C, active human recombinant protein
JMJD2C, active human recombinant protein

Item number: BPS-50105

Active human JMJD2C (GenBank Accession No. BC143571) (amino-acids 2-372) with N-terminal GST tag, MW=69 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: GASC1, KDM4C, GASC-1 protein, Lysine-specific demethylase 4C, Jumonji domain-containing protein 2C, [histone...
Application: Enzyme kinetics, inhibitor screening
MW: 69 kD
686.00€ *
Review
JMJD2A(KDM4A) Active Human Recombinant Protein (1-350)
JMJD2A(KDM4A) Active Human Recombinant Protein (1-350)

Item number: BPS-50123

Replaces JMJD2A, #BPS-50103, a.a. 1-480. Human JMJD2A, also known as JHDM3A and KDM4A (GenBank Accession No. NM_014663) (amino-acids 1-350) with N-terminal His-tag, MW=42 kDa, expressed in an E.coli expression system.
Keywords: KDM4A, JHDM3A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A, [histone H3]-trimethyl-L-lysine(9)...
Application: Enzyme kinetics, inhibitor screening, selectivity profiling
Expressed in: E.coli
Origin: human
MW: 42 kD
686.00€ *
Review
JMJD2A (human, recombinant, His-tagged)
JMJD2A (human, recombinant, His-tagged)

Item number: Cay10336-100

Jumonji Domain Containing 2A (JMJD2A) is a lysine-specific demethylase that catalyzes the demethylation of histone H3 at lysine residues 9 and 36 and histone H1.4 at lysine residue 26. It is composed of the JmjN N-terminal domain, JmjC catalytic domain, two plant homeodomains (PHDs), and two tudor domains that...
Keywords: KDM4A, JHDM3A, Lysine-specific demethylase 4A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A,...
Application: Enzyme activity
MW: 43 kD
642.00€ *
Review
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