- Search results for K06709
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126 products were found matching "K06709"!
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Item number: Cay40120-250
PFI-90 is an inhibitor of lysine demethylases (KDMs). It inhibits KDM3B, KDM4B, KDM5A, and KDM6B by 46.8 to 87.1% when used at a concentration of 10 µM. PFI-90 induces cell death in SJSA-1 osteosarcoma and TC-32 Ewing's sarcoma cancer cells (IC50s = 2 and 1 µM, respectively).Formal Name: 2-(2-pyridinyl)hydrazide,...
Keywords: | 2-(2-pyridinyl)hydrazide, 2-pyridinecarboxylic acid |
Application: | KDM (lysine demethylase) inhibitor |
CAS | 53995-62-3 |
MW: | 214.2 D |
From 64.00€
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Item number: NSJ-RQ7088
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Lysine-specific demethylase 4A is an enzyme that in humans is encoded by the KDM4A gene. This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two...
Keywords: | Anti-KDM4A, Anti-JHDM3A, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A, Anti-[histone... |
Application: | WB, IHC (paraffin), FC, Direct ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
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-10 %
Discount Promotion
Item number: ELK-ELK4412.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KDM4A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KDM4A. Next,...
Keywords: | KDM4A, JHDM3A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A, [histone H3]-trimethyl-L-lysine(9)... |
Application: | ELISA |
Species reactivity: | human |
365.00€
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From 328.50€
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Item number: A300-861A
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no...
Keywords: | Anti-KDM4A, Anti-JHDM3A, EC=1.14.11.-, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A301-478A
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and...
Keywords: | Anti-KDM4B, Anti-JHDM3B, EC=1.14.11.-, Anti-Lysine-specific demethylase 4B, Anti-Jumonji domain-containing protein 2B,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: Cay37431-1
KDM4D-IN-1 is an inhibitor of the histone demethylase jumonji domain-containing 2D (JMJD2D, IC50 = 0.41 µM). It is selective for JMJD2D over JMJD1B, JMJD2B, and jumonji AT rich interactive domain-containing protein 1A (JARID1A, IC50s = >10 µM for all). KDM4D-IN-1 (0.5 µM) decreases the colony formation, migration,...
Keywords: | KDM4D Inhibitor 1, 4,5-dihydro-2-methyl-5-oxo-pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile |
Application: | JMJD2D (KDM4) inhibitor |
CAS | 2098902-68-0 |
MW: | 225.2 D |
From 122.00€
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Item number: A300-885A
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no...
Keywords: | Anti-GASC1, Anti-KDM4C, EC=1.14.11.-, Anti-GASC-1 protein, Anti-Lysine-specific demethylase 4C, Anti-Jumonji... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: Cay13944-5
The jumonji domain-containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are...
Keywords: | NOG, N-(carboxycarbonyl)-glycine |
Application: | PHD1/PHD2 inhibitor |
CAS | 5262-39-5 |
MW: | 147.1 D |
From 43.00€
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Item number: A301-477A
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and...
Keywords: | Anti-KDM4B, Anti-JHDM3B, EC=1.14.11.-, Anti-Lysine-specific demethylase 4B, Anti-Jumonji domain-containing protein 2B,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: BPS-50105
Active human JMJD2C (GenBank Accession No. BC143571) (amino-acids 2-372) with N-terminal GST tag, MW=69 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: | GASC1, KDM4C, GASC-1 protein, Lysine-specific demethylase 4C, Jumonji domain-containing protein 2C, [histone... |
Application: | Enzyme kinetics, inhibitor screening |
MW: | 69 kD |
686.00€
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Item number: BPS-50123
Replaces JMJD2A, #BPS-50103, a.a. 1-480. Human JMJD2A, also known as JHDM3A and KDM4A (GenBank Accession No. NM_014663) (amino-acids 1-350) with N-terminal His-tag, MW=42 kDa, expressed in an E.coli expression system.
Keywords: | KDM4A, JHDM3A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A, [histone H3]-trimethyl-L-lysine(9)... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | E.coli |
Origin: | human |
MW: | 42 kD |
686.00€
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Item number: Cay10336-100
Jumonji Domain Containing 2A (JMJD2A) is a lysine-specific demethylase that catalyzes the demethylation of histone H3 at lysine residues 9 and 36 and histone H1.4 at lysine residue 26. It is composed of the JmjN N-terminal domain, JmjC catalytic domain, two plant homeodomains (PHDs), and two tudor domains that...
Keywords: | KDM4A, JHDM3A, Lysine-specific demethylase 4A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A,... |
Application: | Enzyme activity |
MW: | 43 kD |
642.00€
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