Anti-Interleukin-1 Receptor Type II (IL-1RII) (human)

Anti-Interleukin-1 Receptor Type II (IL-1RII) (human)
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*1
*1 Offer expires 31/03/2021
Item number Size Datasheet Manual SDS Delivery time Quantity Price
109-401-305 1 ml - -

3 - 9 business days*

1,427.00€
 
Protein function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities.... more
Product information "Anti-Interleukin-1 Receptor Type II (IL-1RII) (human)"
Protein function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. [The UniProt Consortium]
Keywords: Anti-IL1R2, Anti-IL1RB
Supplier: Rockland Immunochemicals
Supplier-Nr: 109-401-305

Properties

Application: ELISA, RIA, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: recombinant human IL-1R type II
Format: Serum

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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