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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein... more
Product information "Anti-IL1RN"
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. Protein function: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure. [The UniProt Consortium]
Keywords: | Anti-IRAP, Anti-IL1F3, Anti-IL1RN, Anti-IL-1RN, Anti-IL-1ra, Anti-Anakinra, Anti-ICIL-1RA, Anti-IL1 inhibitor, Anti-Interleukin-1 receptor antagonist protein, IL1RN Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-60596 |
Properties
Application: | WB, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Recombinant protein of human IL1RN |
Database Information
KEGG ID : | K05481 | Matching products |
UniProt ID : | P18510 | Matching products |
Gene ID | GeneID 3557 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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