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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-BV2 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-IL-1RAcP Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-IL-1RAcP"
Anti-IL-1RAcP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This polyclonal antibody has no cross activity to other members in the IL-1 receptor family. Protein function: Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1- dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non- signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand- bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. [The UniProt Consortium]
Keywords: | Anti-IL1RAP, Anti-IL-1R3, Anti-IL-1R-3, Anti-C3orf13, Anti-IL-1RAcP, Anti-Interleukin-1 receptor 3, Anti-IL-1 receptor accessory protein, Anti-Interleukin-1 receptor accessory protein |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-BV2 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | 16 amino acid peptide near the C-terminus of human IL-1RAcP. |
Format: | Purified |
Database Information
KEGG ID : | K04723 | Matching products |
UniProt ID : | Q9NPH3 | Matching products |
Gene ID | GeneID 3556 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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