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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-AMAb91012.25 | 25 µl | - |
7 - 10 business days* |
300.00€
|
|||
ATA-AMAb91012.100 | 100 µl | - |
7 - 10 business days* |
421.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles... more
Product information "Anti-HNRNPC, clone CL2596"
Protein function: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671). [The UniProt Consortium] Validated by genetic and standard strategies. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 55%
Keywords: | Anti-HNRPC, Anti-HNRNPC, Anti-hnRNP C1/C2, Anti-Heterogeneous nuclear ribonucleoproteins C1/C2 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | AMAb91012 |
Properties
Application: | ICC, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | CL2596 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AEMYGSVTEH PSPSPLLSSS (ATA-APrEST85318) |
Database Information
KEGG ID : | K12884 | Matching products |
UniProt ID : | P07910 | Matching products |
Gene ID | GeneID 3183 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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