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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F49550-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F49550-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. HES1 belongs to the basic helix-loop-helix family of... more
Product information "Anti-HES1"
In 1X PBS, pH 7.4, with 0.09% sodium azide. HES1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. HES1 has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. Protein function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage. [The UniProt Consortium]
Keywords: | Anti-hHL, Anti-HES1, Anti-bHLHb39, Anti-BHLHB39, Anti-Hairy homolog, Anti-Hairy-like protein, Anti-Transcription factor HES-1, Anti-Hairy and enhancer of split 1, Anti-Class B basic helix-loop-helix protein 39, HES1 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F49550 |
Properties
Application: | FC, WB, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 9-38 from the human protein was used as the immunogen for this HES1 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K06054 | Matching products |
UniProt ID : | Q14469 | Matching products |
Gene ID | GeneID 3280 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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