Anti-GPR49

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F48169-0.08ML	80 µl		-	-	3 - 10 business days*		361.00€
NSJ-F48169-0.4ML	400 µl		-	-	3 - 10 business days*		772.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. LGR5/GPR49 is an orphan receptor. It may be an... more

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Product information "Anti-GPR49"

In 1X PBS, pH 7.4, with 0.09% sodium azide. LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues. Protein function: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R- spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development. [The UniProt Consortium]

Keywords:	Anti-LGR5, Anti-GPR49, Anti-G-protein coupled receptor 67, Anti-G-protein coupled receptor 49, Anti-G-protein coupled receptor HG38, Anti-Leucine-rich repeat-containing G-protein coupled receptor 5, GPR49 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	F48169

Properties

Application:	FC, WB, IHC, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	A portion of amino acids 443-473 from the human protein was used as the immunogen for this GPR49 antibody.
Format:	Purified