Anti-GPR49 (LGR5, GPR67, Leucine-rich Repeat-containing G-protein Coupled Receptor 5, G-protein Coup

GPR49 is an orphaned member of the glycoprotein hormone receptor subfamily. It is thought to play an important role in growth and differentiation of embyronic tissue. It is highly expressed in the brain, spinal cord, placenta, and skeletal muscle. GPR49 is up-regulated in several cancers. It is also thought to be a target gene activated by Wnt-signaling. , Applications:, Suitable for use in Immunofluorescence, Flow Cytometry, Immunocytochemistry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:100, Flow Cytometry: FACS analysis 1:100, Immunohistochemistry (Paraffin): 1:200, Immunocytochemistry: 1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.