Anti-GITR (TNFRSF18), clone DTA-1

Anti-GITR (TNFRSF18), clone DTA-1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3050-20UG 20 µg - -

3 - 10 business days

NSJ-V3050-100UG 100 µg - -

3 - 10 business days

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. GITR (glucocorticoid-induced... more
Product information "Anti-GITR (TNFRSF18), clone DTA-1"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. GITR (glucocorticoid-induced TNFR-related gene) is a member of the TNF-receptor superfamily, also known as TNFRSF18. It is expressed at low levels on resting T lymphocytes and at high levels on CD25+ CD4+ Tregs. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production as well as MAPKs and NF-??B activation, and abrogate the inhibitory function of CD25+ CD4+ Tregs. In vivo activation of GITR causes development of autoimmune diseases and restores the suppressed immune response. Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. [The UniProt Consortium]
Keywords: Anti-Gitr, Anti-CD357, Anti-Tnfrsf18, Anti-Glucocorticoid-induced TNFR-related protein, Anti-Tumor necrosis factor receptor superfamily member 18, GITR Antibody (TNFRSF18)
Supplier: NSJ Bioreagents
Supplier-Nr: V3050-20UG


Application: FC, IF
Antibody Type: Monoclonal
Clone: DTA-1
Conjugate: No
Host: Rat
Reactivity: Mouse
Immunogen: Mouse CD25+ CD4+ T cells
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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