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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G2021-51D.100 | 100 µl | - | - |
3 - 19 business days* |
734.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of... more
Product information "Anti-GATA4 (GATA binding protein 4, GATA-binding factor 4, Transcription factor GATA-4)"
GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of zinc-finger transcription factors. Members of this family is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. These factors recognize the GATA motif which is present in the promoters of many genes. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:10000, Western Blot: 1:500-1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-GATA-binding factor 4, Anti-Transcription factor GATA-4 |
Supplier: | United States Biological |
Supplier-Nr: | G2021-51D |
Properties
Application: | ELISA, WB |
Antibody Type: | Monoclonal |
Clone: | 10F600 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | Purified recombinant fragment of human GATA4 expressed in E. coli. |
Format: | Ascites |
Database Information
KEGG ID : | K09183 | Matching products |
UniProt ID : | P43694 | Matching products |
Gene ID | GeneID 2626 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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