Anti-GATA4 (GATA binding protein 4,GATA-binding factor 4, Transcription factor)

GATA-4 belongs to the GATA family of transcription factors, which bind to the consensus DNA , sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and , morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-4 , interacts with other transcription factors such as NKX2.5, and myocyte enhancer factor 2 to , regulate cardiac myocyte-specific gene expression. GATA-4 contains 2 zinc finger-binding , domains and migrates at 56kD in SDS-PAGE gels. Human GATA-4 share 93%, 93% and , 92% aa sequence identity with porcine, rat and mouse GATA-4, respectively. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.