Anti-FIP200/RB1CC1

Anti-FIP200/RB1CC1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-574A-T 10 µl (10 µg) -

3 - 9 business days

125.00€
A301-574A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: Involved in autophagy (PubMed:21775823). Regulates early events but also late... more
Product information "Anti-FIP200/RB1CC1"
Protein function: Involved in autophagy (PubMed:21775823). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (PubMed:10769033, PubMed:12221124). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Functions as a DNA-binding transcription factor (PubMed:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:14533007). Plays a crucial role in muscular differentiation (PubMed:12163359). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis. [The UniProt Consortium]
Keywords: Anti-FIP200, Anti-RB1CC1, Anti-KIAA0203, Anti-RB1-inducible coiled-coil protein 1, Anti-FAK family kinase-interacting protein of 200 kDa
Supplier: Bethyl Laboratories
Supplier-Nr: A301-574A-T

Properties

Application: IP
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human (Expected: Gorilla, Chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A301-574A-T maps to a region between residue 250 and 300 human 200 kDa FAK family kinase-interacting protein (RB1-inducible coiled-coil 1) using the numbering given in entry NP_055596.2 (GeneID 9821).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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