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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-536A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-536A | 100 µl | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Involved in autophagy (PubMed:21775823). Regulates early events but also late... more
Product information "Anti-FIP200/RB1CC1"
Protein function: Involved in autophagy (PubMed:21775823). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (PubMed:10769033, PubMed:12221124). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Functions as a DNA-binding transcription factor (PubMed:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:14533007). Plays a crucial role in muscular differentiation (PubMed:12163359). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis. [The UniProt Consortium]
Keywords: | Anti-FIP200, Anti-RB1CC1, Anti-KIAA0203, Anti-RB1-inducible coiled-coil protein 1, Anti-FAK family kinase-interacting protein of 200 kDa |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-536A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: rat, bovine, dog, horse, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, european domestic ferret, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A301-536A-T maps to a region between residue 1544 and 1594 of human 200 kDa FAK family kinase-interacting protein (RB1-inducible coiled-coil 1) using the numbering given in entry NP_055596.2 (GeneID 9821). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K17589 | Matching products |
UniProt ID : | Q8TDY2 | Matching products |
Gene ID | GeneID 9821 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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