Anti-Fibrillarin/Nop1p (Clone: 38F3)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-34-1031-500	500 µl		-		3 - 11 business days*		789.00€

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Protein function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to... more

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Product information "Anti-Fibrillarin/Nop1p (Clone: 38F3)"

Protein function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239). [The UniProt Consortium]

Keywords:	Anti-FBL, Anti-FIB1, EC=2.1.1.-, Anti-Histone-glutamine methyltransferase, Anti-34 kDa nucleolar scleroderma antigen, Anti-rRNA 2'-O-methyltransferase fibrillarin, Monoclonal Antibody to Fibrillarin/Nop1p (Clone: 38F3)
Supplier:	Abeomics
Supplier-Nr:	34-1031

Properties

Application:	IHC, WB
Antibody Type:	Monoclonal
Clone:	38F3
Conjugate:	No
Host:	Mouse
Species reactivity:	pig, rat, mouse, human, bovine
Immunogen:	Yeast nuclear preparations
Format:	Tissue Culture Supernatant