Anti-DISC1

Anti-DISC1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R34282-100UG 100 µg - -

3 - 10 business days*

549.00€
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more
Product information "Anti-DISC1"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Disrupted in schizophrenia 1 Protein function: Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation. [The UniProt Consortium]
Keywords: Anti-DISC1, Anti-KIAA0457, Anti-Disrupted in schizophrenia 1 protein, DISC1 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R34282

Properties

Application: WB, ELISA (peptide)
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human
Immunogen: Amino acids HSEDKRKTPLKVLE were used as the immunogen for this DISC1 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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