Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-AV9 100 µg - -

3 - 9 business days*

Anti-DISC1 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-DISC1"
Anti-DISC1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with DISC1 from other sources has not been determined. Protein function: Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation. [The UniProt Consortium]
Keywords: Anti-DISC1, Anti-KIAA0457, Anti-Disrupted in schizophrenia 1 protein
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-AV9


Application: ELISA, IHC, IFM, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: 18 amino acid synthetic peptide from near the internal region of human DISC1.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Our products are for laboratory research use only: Not for administration to humans!
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