Anti-DDR1 (CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kin

Anti-DDR1 (CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
144439.100 100 µg - -

3 - 19 business days*

659.00€
 
DDR1(Discoidin domain receptor family, member 1) also known as NEP, EDDR1, NTRK4, TRKE, DDR, CAK... more
Product information "Anti-DDR1 (CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kin"
DDR1(Discoidin domain receptor family, member 1) also known as NEP, EDDR1, NTRK4, TRKE, DDR, CAK or RTK6, is a human gene. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen.This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain.The DDR1 gene is mapped on 6p21.33. The fibrillar collagens and immobilized collagen activated DDR1 receptor phosphorylation after prolonged treatment. Bhatt et al. (2000) showed that Ddr1 was highly expressed in the cerebellum of developing and adult mouse brain, and that both Ddr1 and collagen IV were highly expressed in the pial layer of the cerebellar cortex. Cocultures of collagen I- and IV-expressing mouse pial cells with Ddr1-expressing granule cells resulted in granule cell neurite extension. Inhibition of collagen-Ddr1signaling reduced granule cell neurite elongation. UniProt Number: Q08345, Gene ID: DDR1, Applications: Suitable for use in Western Blot. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20?C for one year. After reconstitution, store at 4?C for one month. Can also be aliquoted and stored frozen at -20?C for long term., Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: 144439

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat
Format: Affinity Purified

Database Information

UniProt ID : Q08345 | Matching products

Handling & Safety

Storage: vT
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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