Anti-CYP3A4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG65766.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver... more

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Product information "Anti-CYP3A4"

Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4- hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2- exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599). [The UniProt Consortium]

Keywords:	Anti-CYP3A4, Anti-CYP3A3, Anti-CYPIIIA4, Anti-CYPIIIA3, EC=1.14.13.-, EC=1.14.13.97, EC=1.14.13.67, EC=1.14.13.32, EC=1.14.13.157, Anti-Nifedipine oxidase, Anti-Cytochrome P450 3A4, Anti-Cytochrome P450 3A3, Anti-Cytochrome P450 HLp
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG65766

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Fusion protein of Human CYP3A4
MW:	57 kD
Format:	Antigen Affinity Purified