Anti-CYP3A4

Anti-CYP3A4
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030130.100 100 µl - -

3 - 19 business days*

505.00€
 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450... more
Product information "Anti-CYP3A4"
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., Immunofluorescence: 1:200-1:1000., Flow cytometry: 1:200-1:400., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-CYP3A3, Anti-CYP3A4, Anti-CYPIIIA4, Anti-CYPIIIA3, EC=1.14.13.-, EC=1.14.13.32, EC=1.14.13.67, EC=1.14.13.97, EC=1.14.13.157, Anti-Nifedipine oxidase, Anti-Cytochrome P450 3A3, Anti-Cytochrome P450 HLp, Anti-Cytochrome P450 3A4
Supplier: United States Biological
Supplier-Nr: 030130

Properties

Application: ELISA, FC, IHC, WB
Antibody Type: Monoclonal
Clone: 13B208
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human CYP3A4 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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