- Search results for K17689
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87 products were found matching "K17689"!
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Item number: Cay40332-1
Voriconazole-d3 N-oxide is intended for use as an internal standard for the quantification of voriconazole N-oxide (Cay-28047) by GC- or LC-MS. Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole (Cay-15633). It is formed via oxidation of voriconazole by the cytochrome P450 (CYP)...
Keywords: | (alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol-d3,... |
Application: | GC-MS, LC-MS internal standard, quantification, major voriconazole metabolite |
CAS | 1217851-84-7 |
MW: | 368.3 D |
From 481.00€
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Item number: Cay38301-1
11beta-hydroxy Testosterone is a metabolite of testosterone. It is formed from testosterone primarily by the cytochrome P450 (CYP) isoform CYP3A4.Formal Name: 11beta,17beta-dihydroxy-androst-4-en-3-one. CAS Number: 1816-85-9. Synonyms: NSC 12168. Molecular Formula: C19H28O3. Formula Weight: 304.4. Purity: >95%....
Keywords: | NSC 12168, 11beta,17beta-dihydroxy-androst-4-en-3-one |
Application: | Testosterone metabolite |
CAS | 1816-85-9 |
MW: | 304.4 D |
From 34.00€
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Item number: Cay40122-1
6beta-hydroxy Triamcinolone acetonide is a metabolite of the synthetic corticosteroid triamcinolone acetonide (Cay-18026). It is formed from triamcinolone acetonide by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7. 6beta-hydroxy Triamcinolone acetonide has been found in wastewater effluent.Formal...
Keywords: | 6beta-hydroxy TrA, 9-fluoro-6beta,11beta,21-trihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione |
Application: | Triamcinolone acetonide metabolite |
CAS | 3869-32-7 |
MW: | 450.5 D |
636.00€
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Item number: Cay39807-1
6-hydroxy Buspirone is an active metabolite of the anxiolytic buspirone. It is formed from buspirone by the cytochrome P450 (CYP) isoform CYP3A4. 6-hydroxy Buspirone binds to the serotonin (5-HT) receptor subtype 5-HT1A in rat hippocampus and dorsal raphe (EC50s = 4 and 1 µM, respectively) and is a dopamine D2, D3,...
Keywords: | BMS-52821, BMY 28674, 6-hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione |
Application: | Active buspirone metabolite |
CAS | 125481-61-0 |
MW: | 401.5 D |
From 314.00€
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Item number: ELK-ELK3947.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CYP3A4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CYP3A4....
Keywords: | CYP3A3, CYPIIIA3, CYPIIIA4, Nifedipine oxidase, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome... |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: Cay16115-500
N-Acetyl-4-benzoquinone imine (NAPQI) is a cytochrome P450 3A4 and 2E1 metabolite of acetaminophen that can be toxic to the liver when acetaminophen is consumed in large doses. At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of...
Keywords: | N-Acetyl-p-benzoquinonimine, NAPQI, N-(4-oxo-2,5-cyclohexadien-1-ylidene)-acetamide |
Application: | Paracetamol metabolite |
CAS | 50700-49-7 |
MW: | 149.2 D |
From 158.00€
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Item number: Cay22099-2.5
6beta-hydroxy Dexamethasone is an active metabolite of the synthetic glucocorticoid dexamethasone (Cay-11015). It is formed from dexamethasone by the cytochrome P450 (CYP) isoform CYP3A4. 6beta-hydroxy Dexamethasone (1 mg/kg) reduces cortisol (hydrocortisone, Cay-20739) production in rats.Formal Name:...
Keywords: | 6beta-hydroxydexamethasone, 6-hydroxyDEX, 6OH-DEX,... |
Application: | Dexamethasone active metabolite |
CAS | 55879-47-5 |
MW: | 408.5 D |
374.00€
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Item number: Cay38159-10
7alpha-hydroxy-3-oxo-5beta-Cholan-24-oic acid is a metabolite of chenodeoxycholic acid (Cay-35346, Cay-10011286). It is formed from chenodeoxycholic acid primarily by the cytochrome P450 (CYP) isoform CYP3A4 but also by CYP3A5 and other P450 enzymes at lower rates.Formal Name:...
Keywords: | 3-keto-7alpha-hydroxy-5beta-Cholanic Acid, 3-Oxochenodeoxycholic Acid, (5beta)-7alpha-hydroxy-3-oxo-cholan-24-oic acid |
Application: | Chenodeoxycholic acid metabolite |
CAS | 4185-00-6 |
MW: | 390.6 D |
From 117.00€
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Item number: Cay28047-1
Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole (Cay-15633). It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.Formal Name:...
Keywords: | UK 121265,... |
Application: | Major voriconazole metabolite |
CAS | 618109-05-0 |
MW: | 365.3 D |
From 218.00€
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Item number: Cay18749-1
SB 202190 (Cay-10010399) and SB 203580 (Cay-13067) are potent, selective inhibitors of the MAP kinases p38alpha and p38beta. SB 202474 is a structural analog of SB 202190 and SB 203580 that is used as a negative control in studies of p38 inhibition.Formal Name:...
Keywords: | 4-[4-ethyl-2-(4-methoxyphenyl)-1H-imidazol-5-yl]-pyridine |
Application: | Irreversible CYP3A inhibitor |
CAS | 172747-50-1 |
MW: | 279.3 D |
189.00€
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Item number: Cay17923-25
Naringin is a natural flavanone glycoside formed from naringenin and neohesperidose. It undergoes extensive metabolism in the liver, giving rise to naringenin and other bioactive metabolites that have anti-oxidant, anti-inflammatory, and anti-apoptotic effects. Naringin is a weak inhibitor of CYP3A4, providing 14%...
Keywords: | NSC 5548,... |
Application: | Weak CYP3A4 inhibitor |
CAS | 10236-47-2 |
MW: | 580.5 D |
From 50.00€
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Item number: Cay15901-1
Norhydrocodone (Cay-15901) is an analytical reference material categorized as an opioid. It is an active metabolite of hydrocodone (Cay-ISO60144). This product is intended for research and forensic applications.Formal Name: 4,5alpha-epoxy-3-methoxy-morphinan-6-one, monohydrochloride. CAS Number: 71968-04-2....
Keywords: | 4,5alpha-epoxy-3-methoxy-morphinan-6-one, monohydrochloride |
Application: | Analytical reference material, Opioid, Active hydrocodone metabolite |
CAS | 71968-04-2 |
MW: | 321.8 D |
From 109.00€
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