| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG54674.50 | 50 µg | - | - |
6 - 14 business days* |
625.00€
|
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [The UniProt Consortium]
| Keywords: | Anti-HM89, Anti-FB22, Anti-LCR1, Anti-CXCR4, Anti-LAP-3, Anti-CD184, Anti-Fusin, Anti-LESTR, Anti-NPYRL, Anti-CXC-R4, Anti-CXCR-4, Anti-SDF-1 receptor, Anti-LPS-associated protein 3, Anti-C-X-C chemokine receptor type 4 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG54674 |
Properties
| Application: | ELISA, FC, ICC, IF, IHC (paraffin), IHC (frozen), IP, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | Synthetic peptide around 14 aa (N-terminus) of Human CXCR4 protein (NP_001008540.1) |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K04189 | Matching products |
| UniProt ID : | P61073 | Matching products |
| Gene ID : | GeneID 7852 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Our products are for laboratory research use only: Not for administration to humans!
