Anti-Cul5

Anti-Cul5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-173A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-173A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-173A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein)... more
Product information "Anti-Cul5"
Protein function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor. [The UniProt Consortium]
Keywords: Anti-CUL5, Anti-CUL-5, Anti-VACM1, Anti-VACM-1, Anti-Cullin-5, Anti-Vasopressin-activated calcium-mobilizing receptor 1
Supplier: Bethyl Laboratories
Supplier-Nr: A302-173A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rat, Rabbit, Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A302-173A-T maps to a region between residue 1 and 50 of human cullin-5 using the numbering given in entry NP_003469.2 (GeneID 8065).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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