Anti-Cul5

Item number	Size	Manual	Delivery time	Price
A302-173A-T	20 µl (2 blots)	-	3 - 9 business days*	131.00€
A302-173A-M	100 µl (10 blots)	-	3 - 9 business days*	313.00€
A302-173A	100 µl (100 µg)	-	3 - 9 business days*	465.00€

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Protein function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein)... more

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Product information "Anti-Cul5"

Protein function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor. [The UniProt Consortium]

Keywords:	Anti-CUL5, Anti-CUL-5, Anti-VACM1, Anti-VACM-1, Anti-Cullin-5, Anti-Vasopressin-activated calcium-mobilizing receptor 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-173A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Reactivity:	Human, Mouse (Expected: Rat, Rabbit, Orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A302-173A-T maps to a region between residue 1 and 50 of human cullin-5 using the numbering given in entry NP_003469.2 (GeneID 8065).
Format:	Antigen Affinity Purified