Anti-Cullin-5, NT (CUL-5)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
100-401-A05	100 µl		-	-	6 - 10 business days*		684.00€

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Protein function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein)... more

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Product information "Anti-Cullin-5, NT (CUL-5)"

Protein function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor. [The UniProt Consortium]

Keywords:	Anti-CUL5, Anti-CUL-5, Anti-VACM1, Anti-VACM-1, Anti-Cullin-5, Anti-Vasopressin-activated calcium-mobilizing receptor 1
Supplier:	Rockland Immunochemicals
Supplier-Nr:	100-401-A05

Properties

Application:	ELISA, IHC, IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	synthetic peptide corresponding to amino acids 4-18 of human Cul5 (N-terminus)
Format:	Serum