Anti-CREBBP / KAT3A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG57967.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Acetylates histones, giving a specific tag for transcriptional activation. Also... more

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Product information "Anti-CREBBP / KAT3A"

Protein function: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK- ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902). [The UniProt Consortium]

Keywords:	Anti-CBP, Anti-CREBBP, Anti-CREB-binding protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57967

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide corresponding to a sequence within aa. 100-200 of Human CREBBP (NP_004371.2)
MW:	265 kD
Format:	Affinity Purified